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Single oral doses of labetalol HCl administered to patients with coronary artery disease had no significant effect on sinus rateintraventricular conductionor QRS durationThe atrioventricularA-Vconduction time was modestly prolonged in two of seven patientsIn another studyIV labetalol HCl slightly prolonged A-V nodal conduction time and atrial effective refractory period with only small changes in heart rateThe effects on A-V nodal refractoriness were inconsistent.
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