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Malignant lymphomasStages III and IV of the Ann Arbor staging systemHodgkin’s diseaselymphocytic lymphomanodular or diffusemixed-cell type lymphomahistiocytic lymphomaBurkitt’s lymphoma multiple myeloma leukemiaschronic lymphocytic leukemiachronic granulocytic leukemiait is usually ineffective in acute blastic crisisacute myelogenous and monocytic leukemiaacute lymphoblasticstem-cellleukemiacyclophosphamide given during remission is effective in prolonging its durationmycosis fungoidesadvanced diseaseneuroblastomadisseminated diseaseadenocarcinoma of the ovary retinoblastoma carcinoma of the breast.
Continued use of cyclophosphamide is contraindicated in patients with severely depressed bone marrow functionCyclophosphamide is contraindicated in patients who have demonstrated a previous hypersensitivity to itSee WARNINGS and PRECAUTIONS
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