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Oxybutynin chloride exerts a direct antispasmodic effect on smooth muscle and inhibits the muscarinic action of acetylcholine on smooth muscleOxybutynin chloride exhibits only one fifth of the anticholinergic activity of atropine on the rabbit detrusor musclebut four to ten times the antispasmodic activityNo blocking effects occur at skeletal neuromuscular junctions or autonomic gangliaantinicotinic effects
Each tablet contains 2.5 mg or 5mg of the active substanceoxybutynin hydrochlorideThe other ingredients lactosecellulosecalcium stearate and indigo carmineE132
Before using Ditropan XLtell your doctor if you have glaucomaliver or kidney diseasean enlarged prostatemyasthenia gravisulcerative colitisa blockage in your stomach or intestinesor a stomach disorder such as gastroesophageal reflux diseaseGERDor slow digestion.
DITROPAN should be used with caution in patients who have gastroesophageal reflux and/or who are concurrently taking drugssuch as bisphosphonatesthat can cause or exacerbate esophagitis.
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