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Premenopausal women who have a high risk of breast cancer due to certain changes in the brca1 and brca2 genes may choose to have a risk-reducing oophorectomythe removal of both ovaries when there are no signs of cancerThis decreases the amount of estrogen made by the body and lowers the risk of breast cancerRisk-reducing oophorectomy also lowers the risk of breast cancer in normal premenopausal women and in women with an increased risk of breast cancer due to radiation to the chestHoweverit is very important to have a cancer risk assessment and counseling before making this decisionThe sudden drop in estrogen levels may cause the symptoms of menopause to beginThese include hot flashestrouble sleepinganxietyand depressionLong-term effects include decreased sex drivevaginal drynessand decreased bone density.
Taking estrogen-only hormone therapy after hysterectomyselective estrogen receptor modulatorsor aromatase inhibitors and inactivators.
A personal history of invasive breast cancerductal carcinoma in situdcisor lobular carcinoma in situlcisA personal history of benignnoncancerbreast disease.
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