That was that the paxil withdrawal issue was not formally studied during the tests.
Information about Paxil.
A very serious allergic reaction to this drug is rareHoweverget medical help right away if you notice any symptoms of a serious allergic reactionincludingrashitching/swellingespecially of the face/tongue/throatsevere dizzinesstrouble breathing.
Postmarketing reportsDrug-induced liver injuryelevated liver function testshepatic failureRef]
Extrapyramidal symptoms such as akathisiabradykinesiacogwheel rigiditydystoniahypertoniaand oculogyric crisis have been associated with concomitant pimozide therapy.
Doctors prescribe Paxil for the treatment of not only depression and anxiety disordersbut also obsessive-compulsive disorder and post-traumatic stress disorderIn some casesit may also be used for the treatment of premenstrual dysphoric disorder or PMDD.
Compounds of structure2are prepared by reaction of an arecoline analogue of structure(4with an organometallic compound containing an X-substituted phenyl groupsuch as a compound of structure3STR1Suitably the compound of structure3is a Grignard reagentwhere M is magnesium and Y is a halogen atomor M may be a Group II metal and Y is a halogen atom or a second X-substituted phenyl groupWhen structure3is a Grignard reagentthe reaction is carried out either in a suitable non-ether solventtypically a hydrocarbon or a non-reactive chlorinated hydrocarbonor in a mixture of such a solvent with diethyl etherCompounds of structure2are important intermediates in the preparation of inter alia paroxetine.
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