Use caution, and monitor therapeutic effects of prednisolone when coadministered with vemurafenib.
Information about Prednisolone.
The dose depends on your illness and whether you are taking prednisolone as a short course or for longer.
If you have used prednisolone regularly for a long time or in high dosesyou may have withdrawal symptoms if the drug is suddenly stoppedTo prevent withdrawal symptomssuch as weaknessweight lossnauseamuscle painheadachetirednessdizzinessyour doctor may reduce your dose graduallyConsult your doctor or pharmacist for more detailsand report any withdrawal reactions right awaySee also Precautions section.
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Alternate-Day Therapy is a corticosteroid dosing regimen in which twice the usual daily dose of corticoid is administered every other morningThe purpose of this mode of therapy is to provide the patient requiring long-term pharmacologic dose treatment with the beneficial effects of corticoids while minimizing certain undesirable effectsincluding pituitary-adrenal suppressionthe Cushingoid statecorticoid withdrawal symptomsand growth suppression in children.
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