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Since Rocaltrolcalcitriolis believed to be the active hormone which exerts vitamin D activity in the bodyadverse effects arein generalsimilar to those encountered with excessive vitamin D intakeiehypercalcemia syndrome or calcium intoxicationdepending on the severity and duration of hypercalcemiasee WARNINGSBecause of the short biological half-life of calcitriolpharmacokinetic investigations have shown normalization of elevated serum calcium within a few days of treatment withdrawaliemuch faster than in treatment with vitamin D 3 preparations.
The effectiveness of treatment depends in part on an adequate daily intake of calciumwhich should be augmented by dietary changes or supplements if necessaryThe capsules should be swallowed with a little water.
Before you begin using a medicationbe sure to inform your doctor of any medical conditions or allergies you may haveany medications you are takingwhether you are pregnant or breast-feedingand any other significant facts about your healthThese factors may affect how you should use this medication.
Patients with normal renal function taking Rocaltrolcalcitriolshould avoid dehydrationAdequate fluid intake should be maintained.
Thiazides are known to induce hypercalcemia by the reduction of calcium excretion in urineSome reports have shown that the concomitant administration of thiazides with Rocaltrolcalcitriolcauses hypercalcemiaThereforeprecaution should be taken when coadministration is necessary.
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rocaltrol may be taken with or without food.0